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Image Search Results
Journal: Blood
Article Title: SOX11 augments BCR signaling to drive MCL-like tumor development
doi: 10.1182/blood-2018-02-832535
Figure Lengend Snippet: SOX11 expression leads to clonal expansion of B cells. (A) Deep sequencing of the genomic DNA from B1a cells showing increased IgH gene clonality in Tg-SOX11 mice vs WT mice. (B) Decreased total productive rearrangements in the BCR repertoire of B1a cells of Tg-SOX11 mice vs WT mice showing a decrease in IgH gene diversity. (C) Frequency of the top 10 rearrangements compared with all other rearrangements of the IgH locus in B1a cells showing clonality in 2 Tg-SOX11 mice and oligoclonality in 2 Tg-SOX11 mice vs normal IgH diversity in the 2 WT mice. (D) Productive frequency of the top 100 IgH gene rearrangements shows loss of IgH diversity in all Tg-SOX11 mice (N = 4) as compared with WT mice (N = 2). In the histogram, each color represents a unique IgH clone, whereas the numerals represent the frequency of top clone in each mouse.
Article Snippet: We conducted next-generation deep sequencing of the genomic
Techniques: Expressing, Sequencing
Journal: Metabolites
Article Title: What Has Longitudinal ‘Omics’ Studies Taught Us about Irritable Bowel Syndrome? A Systematic Review
doi: 10.3390/metabo13040484
Figure Lengend Snippet: The characteristics and key findings of the studies reviewed (arranged alphabetically by the first author’s last name).
Article Snippet: Ankersen, 2021 [ ] , Denmark , 34 IBS patients (either IBS-D or IBS-M) randomised to receive either web-based low FODMAP diet intervention or probiotic; Rome III criteria for diagnosis , Stool sample ,
Techniques: Biomarker Discovery, Microarray, Real-time Polymerase Chain Reaction, Functional Assay, Expressing, Next-Generation Sequencing, Bacteria, Gene Expression, Genome Wide, Probiotics, Isolation, Amplification, Sequencing, Starch, Fluorescence, FACS, Concentration Assay, Control, Clinical Proteomics, RNA Sequencing, Modification